Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors inside the central nervous technique, conolidine modulates alternate molecular targets. A Science Advances study found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://socialfactories.com/story6335861/alternative-natural-pain-relief-to-replace-traditional-painkillers-for-dummies