Abstract Background Oncogenesis rewires signaling networks to confer a fitness advantage to malignant cells. For instance. the B16F0 melanoma cell model creates a cytokine sink for Interleukin-12 (IL-12) to deprive neighboring cells of this important anti-tumor immune signal. While a cytokine sink provides an indirect fitness advantage. https://www.getpureroutine.com/top-deal-chromasilk-7-35-7gm-golden-mahogany-blonde-online-sale-best-super/