2. Histamine Receptor Antagonism: Some sedatives, for instance antihistamines, exert their sedative effects by blocking histamine receptors during the Mind, specifically H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t combine sedatives alongside one another or with other drugs https://sedativesdrugs19763.xzblogs.com/73920029/sedative-drugs-for-pain-relief-best-options-recommendations