Gastrointestinal (GI): NSAIDs that block COX-one activity have correlations with GI problems as a result of inhibition on the synthesis of gastroprotective brokers such as PGE2 and also other prostaglandins. This inhibition causes lowered mucin output by gastric epithelial cells, much less bicarbonate secretion, and less epithelial mobile turnover, among https://archbishopb789zxx0.wikibestproducts.com/user